Defective α tectorin may involve tectorial membrane in familial Meniere diseaseWe are happy to announce that we have a new paper published in Clinical and Translational Medicine: "Defective α-tectorin may involve tectorial membrane in familial Meniere disease". Although there have been considerable advances in recent years, the contribution of genetic factors to Meniere's disease (MD) is not yet fully understood.The results of the present study add new evidence to support the involvement of α-tectorin in the pathophysiology of MD. We report four multicase MD families carrying rare missense heterozygous variants (F1–F3) and a short deletion (F4) in the coding region of the TECTA gene. Variants in this gene were also found in two additional families with one MD patient and relatives with partial syndromes carrying a missense heterozygous variant (F5) and a short deletion (F6). More information can be found here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162437/ 

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