A special issue on "Novel Treatments and Diagnosis for Chronic Tinnitus" is organised by UNITI members Dr. Winfried Schlee and Prof. Dr. Jose A. Lopez-Escamez. The challenge is to improve the diagnostic procedures of tinnitus and assign the appropriate treatment or combination of treatments to the individual tinnitus patient. With this Special Issue, we want to concentrate on innovative diagnostic procedures and novel treatment strategies that aim to improve the patient journey from diagnosis to the best-suited therapeutic approach for the individual patient. In this respect, research papers on individualized treatment decisions and decision support systems are also strongly encouraged. Original research papers and systematic reviews of high quality are welcome.