Unification of Treatments and Interventions for Tinnitus Patients (UNITI)
UNITI results
UNITI project finished in September 2023. It’s overall aim was to deliver a predictive computational model based on existing and longitudinal data attempting to address the question which treatment approach is optimal for a specific patient based on specific parameters. Clinical, epidemiological, medical, genetic and audiological data, including signals reflecting ear-brain communication, were analysed from existing databases. Predictive factors for different patient groups were extracted and their prognostic relevance were tested in a randomized controlled trial (RCT) in which different groups of patients underwent a combination of therapies targeting the auditory and central nervous systems.
Click here to learn more about the UNITI results.
A new publication of the swedish research team of Karolinska Institutet, led by Christopher Cederroth, highlight the importance of considering tinnitus severity and sex in the design of large genetic studies to optimize diagnostic approaches and ultimately improve therapeutic interventions.
The open acces article "Sex-Dependent Aggregation of Tinnitus in Swedish Families" has now been published in J. Clin. Med. 2020, 9(12), 3812; https://doi.org/10.3390/jcm9123812
Data and analysis scripts of the UNITI-RCT results are currently available upon request (stefan.schoisswohl@klinik.uni-regensburg.de).